Schein: Down goes Deon
Saturday, September 17, 2011
Improving sleeping sickness make you nurvous
Adding another drug to an arsenic-based medicine used against African sleeping sickness and researchers from Britain and France may have found a way to remove the cure less toxic. The standard drug, called melarsoprol, is administered by intravenous injection and it is effective against the parasite that causes the disease. But it also kills about 5 percent of patients receiving it, by some estimates. Combining melarsoprol with compounds called cyclodextrins allowed mice infected with sleeping sickness to take the drugs orally but getting more gradual release of its toxic cargo. The approach meant melarsoprol was able to reach the parasite in the nervous system. without lethal side effects and it was researchers report.
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